ZHOU Xirong ^{1, 2}, HUANG Lingyan ^{1, 2}, ZENG Weimin ^{1, 2}, LI Jiayin ^{1, 3}, HUANG Jianfeng ³
(1. Monalisa Group Co., Ltd., Foshan 528211, Guangdong, China; 2. China Light Industry Key Laboratory of Inorganic Materials, Foshan 528211, Guangdong, China; 3. School of Materials Science and Engineering, Shaanxi Science & Technology University, Xi’an 710021, Shaanxi, China)

Abstract: Calcium phosphate is an excellent inorganic antibacterial carrier, with high temperature resistance and good biocompatibility. Silver-doped calcium phosphate powder was synthesized by using a one-step wet mothed, with Ca(OH)₂, H₃PO₄ and AgNO₃ as the raw materials and NH₃•H₂O to adjust pH value of reaction system. XRD and EDS results indicated that the main crystal phase was tricalcium phosphate (β-TCP), as the Ca/P molar ratio was 1.5, pH value was 7.4. It was found that the release performance of the silver-doped calcium phosphate was strongly dependent on the preparation conditions, the mass of fraction of silver and application environment. The calcium phosphate powder with 3.30 wt.% silver had good antibacterial performance for Escherichia coli, Staphylococcus albus and Bacillus subtilis them, with the average width-diameter ratios of bacteriostatic zone to be 0.317.
Key words: calcium phosphate; sustained release; antibacterial material; antibacterial property